271 games like SpaceChem

Featuring some truly fowl images indeed. Pixel Puzzles 2: Birds is a traditional style jigsaw puzzle game, with crabs scurrying around so WATCH YOUR FINGERS!!! The Pixel Puzzles series has been treated to a complete rebuild from the ground up, resulting in Pi...

What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you...

Gardenscapes is a casual puzzle game developed by Playrix where players embark on a journey to restore and beautify a neglected garden. The protagonist, Austin the butler, inherits a sprawling but dilapidated garden and mansion and enlists the player's help to...

Eets Munchies is a reimagining of the award-winning puzzle game by Klei Entertainment. Featuring gorgeous animation and ridiculous creatures, players help an adorable hungry creature devour cake in increasingly devious puzzles. Replay the game forever with th...

Splice is a puzzler where you are microbes that you "splice" to create a specific strand structure in a few amount of moves.

Pixel Puzzles Ultimate, Bringing puzzles to the digital age.

FTL: Faster Than Light is a single-player strategy game with roguelike design. The player commands a spaceship from a top-down view, managing systems such as weapons, engines, shields, and life support while recruiting crew and upgrading the vessel. The ship t...

Anomaly Defenders is the closing installment of the Anomaly series. The original incarnation of the Tower Offense sub-genre had players controlling humans fighting alien invaders. Now, the tables have turned. The human counterattack is underway and the alien h...

Oil Rush is a naval strategy game that takes place in a world where nuclear war has melted the ice caps, changing the face of the planet forever. Oil Rush offers unique gameplay, avoiding micromanagement of every single unit, while still providing full control...

Sid Meier's Civilization V is a turn-based strategy game in which players lead a civilization from the ancient era through the future. Players found cities, research technologies, build improvements, train military units, and engage in diplomacy with AI or hum...

Fate of the World is a dramatic global strategy game that puts all our futures in your hands. The game features a dramatic set of scenarios based on the latest science covering the next two centuries. You must manage a balancing act of protecting the Earth’s r...

Outer Wilds is a critically-acclaimed and award-winning open world mystery about a solar system trapped in an endless time loop. The newest member of the space program in a small village on the planet Timber Hearth, the player navigates a space shuttle and tra...

Half-Life 2: Episode Two is a first-person shooter set in the aftermath of the Citadel's destruction. Players control Gordon Freeman as he and Alyx Vance travel through forests and underground tunnels toward a resistance base, facing Combine forces and new ene...

Join Dr. Rosalene and Dr. Watts as they enter a patient named Johnny's mind on his death bed to grant his final request. Watch, interact, and change the past as Johnny's life unfolds before you and takes you on a magical journey inside one's head that asks the...

In Edge players take direct control of the cube and roll their way around the game's dozens of levels. Search for all the prisms and find the shortcuts to improve your times.

Half-Life is a 1998 first-person shooter (FPS) game developed by Valve Corporation and published by Sierra Studios for Windows. It was Valve's debut product and the first game in the Half-Life series. The player assumes the role of Gordon Freeman, a theoretica...

Dead Space is a 2008 science fiction survival horror video game developed by EA Redwood Shores (now Visceral Games) for Microsoft Windows, PlayStation 3 and Xbox 360. The game was released on all platforms through October 2008. The game puts the player in cont...

XCOM: Enemy Unknown is a turn-based tactics game with a strategic management layer, and a reimagining of the 1994 strategy title UFO: Enemy Unknown. Players lead a squad of soldiers through turn-based combat missions against alien forces, using cover, position...

XCOM 2 is the sequel to XCOM: Enemy Unknown, the 2012 award-winning strategy game of the year. Earth has changed and is now under alien rule. Facing impossible odds you must rebuild XCOM, and ignite a global resistance to reclaim our world and save humanity.

BioShock is a horror-themed first-person shooter set in a steampunk underwater dystopia. The player is urged to turn everything into a weapon: biologically modifying their own body with Plasmids, hacking devices and systems, upgrading their weapons, crafting n...