198 games like Bio-Defense

Change is an emotional homeless survival experience set in a randomly generated city with rogue-like elements. Explore, survive, earn perks, find items and more to develop your character and escape to a new life.

Force of Nature is an indie open world sandbox game with fighting, crafting, building and farming systems.

The Blackout Club is a first-person co-op horror game centered around a group of teenage friends investigating a monstrous secret beneath the skin of their small town. 1-4 players explore procedurally-generated missions against a fearsome enemy you can only se...

The next installment in the critically acclaimed “State of Decay” franchise immerses you in an all-new, multiplayer zombie survival fantasy. Build a lasting community, working with other players or solo to overcome challenges while exploring your own unique st...

A vibrant first-person survival adventure, Among Trees is set in a colorful wilderness world teeming with life. SETTLE DOWN IN YOUR NEW HOME This is your little wood cabin. Located in the heart of a lush forest, the cabin is expandable: build new rooms and un...

A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.

Minecraft focuses on allowing the player to explore, interact with, and modify a dynamically generated map made of one-cubic-meter-sized blocks. In addition to blocks, the environment features plants, mobs, and items. Some activities in the game include mining...

Fortnite is a free-to-play online game where you and your friends fight to be the last one standing in Battle Royale, join forces to make your own Creative games, or catch a live show at Party Royale.

The Long Journey Home combines the endless freedom of space with a new open questing system that always leaves you in command. Deliver the stranded Glukkt to his homeworld as he asks, or to your new slaver friends? Attempt to make allies with everyone, or pin...

Breach & Clear brings deep tactical strategy simulation to PC, Mac and Linux! Build your Special Operations team, plan and execute advanced missions, and own every angle. Choose your real-world squad -- US Army Rangers, Germany's KSK, Canada’s JTF2, UK SAS, a...

In 30 days, help is coming... A mysterious radio transmission claims that help is inbound. You are Jacob Solomon: leader of a makeshift team trying to survive the aftermath of a devastating asteroid collision. The world you once knew is no more – buried deep...

Minecraft focuses on allowing the player to explore, interact with, and modify a dynamically-generated map made of one-cubic-meter-sized blocks. In addition to blocks, the environment features plants, mobs, and items. Some activities in the game include mining...

Frostpunk, the newest title from the creators of This War of Mine, is a society survival game where heat means life and every decision comes at a price. In an entirely frozen world, people develop steam-powered technology to oppose the overwhelming cold. You f...

Fallout Shelter puts you in control of a state-of-the-art underground Vault from Vault-Tec. Build the perfect Vault, keep your Dwellers happy, and protect them from the dangers of the Wasteland. Vault-Tec has provided the tools, but the rest is up to you. Wha...

Don’t Starve is an uncompromising wilderness survival game full of science and magic. Enter a strange and unexplored world full of strange creatures, dangers, and surprises. Gather resources to craft items and structures that match your survival style.

You will be mining resources, researching technologies, building infrastructure, automating production and fighting enemies. Use your imagination to design your factory, combine simple elements into ingenious structures, apply management skills to keep it work...

Project Zomboid is the ultimate in zombie survival. Alone or in MP: you loot, build, craft, fight, farm and fish in a struggle to survive. A hardcore RPG skillset, a vast map, a massively customisable sandbox and a cute tutorial raccoon await the unwary. So ho...

In This War Of Mine you do not play as an elite soldier, rather a group of civilians trying to survive in a besieged city; struggling with lack of food, medicine and constant danger from snipers and hostile scavengers. The game provides an experience of war se...

As the lone survivor of a passenger jet crash, you find yourself in a mysterious forest battling to stay alive against a society of cannibalistic mutants. Build, explore, survive in this terrifying first person survival horror simulator.

Escape from Tarkov is a hardcore and realistic online first-person action RPG/Simulator with MMO features and story-driven walkthrough.